Top 14 Venture Capital Firms for Enterprise Startups
Finding the right VC for your enterprise startup is crucial. Here are 14 active firms, and once funded, our platform helps you manage your capital.
Rho Editorial Team
When you're preparing to raise capital for your Enterprise business, knowing which investors truly understand your space is critical. Pitching to the right people saves time and increases your chances of finding a partner who can provide more than just money.
To help you find the right fit, our team at Rho has put together this overview of top venture capital firms focused on Enterprise software and SaaS. Think of it as a starting point for identifying investors who are actively funding companies like yours.
Rho provides access to business banking, corporate cards, and bill pay — built for startup teams moving fast.
Key Takeaways
Securing venture funding for your Enterprise startup is about finding a strategic partner with industry expertise, not just a source of capital.
Top VCs active in the Enterprise software space include notable backers like Glasswing Ventures, LRVHealth, M25, and G20 Ventures.
After you close a round, Rho helps you manage your capital with fast business banking, corporate cards, and automated bill pay.
Which VC Firms in Enterprise Are Right for Your Stage?
From your earliest funding rounds to preparing for an exit, connecting with the right investors is key. We've organized this overview to show you which Enterprise-focused VC firms invest at each stage.
Pre-seed and Seed VC Firms in Enterprise
Pre-seed and seed rounds provide your first institutional capital, designed to help you find product-market fit and build your initial team. For founders of enterprise software startups, some SaaS focused early stage VC firms to know are M25, a highly active investor in the Midwest, along with the accelerator Sputnik ATX and seed-specialist Frontures.
Early Stage VC Firms in Enterprise
Early-stage funding, typically Series A and B, is for scaling your go-to-market strategy and expanding your team after you've established initial traction. Some technology VC firms with a strong early-stage enterprise focus include the Boston-based Glasswing Ventures, which backs AI-driven startups, as well as Tech Square Ventures and Brick & Mortar Ventures.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Late Stage VC Firms in Enterprise
Late-stage rounds provide growth capital to established companies preparing for an IPO or acquisition, focusing on market leadership and profitability. Examples of late-stage venture capital firms include corporate VCs like Capital One Ventures and Dell Technologies Capital, and expansion-focused funds such as Lumia Capital.
Keep in mind that many VC firms invest across all startup funding stages, offering support from a company's inception through to its exit.
To help with your search, here is our overview of top VC firms that focus on Enterprise software, complete with details on their investment stages, geographic preferences, and what makes each firm a noteworthy option for founders.
1. Glasswing Ventures
Based in Boston, Glasswing Ventures is an early-stage venture capital firm that invests in startups applying AI and other frontier technologies. Their primary focus is on the enterprise and cybersecurity markets.
The firm has a clear thesis around backing companies with deep technical foundations to solve complex business problems. A notable exit includes their investment in Zylotech, a B2B customer-data platform that was acquired by Terminus.
Glasswing Ventures is a strong potential partner if you are an early-stage founder using AI to build solutions for enterprise or security customers. Their portfolio suggests a preference for technically ambitious products.
Investment stages: Seed, Early Stage Venture
Industries of focus: Enterprise Software, AI, Cybersecurity, Frontier Technology
Geographical presence: Boston, MA
Founded: 2016
Notable portfolio companies: Black Kite, ChaosSearch, Allure Security
Portfolio size: 71 investments
You can refer to their website here.
2. LRVHealth
LRVHealth is a venture capital firm with deep roots in the healthcare industry, operating from its Boston office since 2000. Their team is made up of experienced healthcare investors, operators, and advisors, giving them an insider's perspective on the market.
The firm focuses on enterprise software, medical devices, and security solutions built for the healthcare sector. Their portfolio highlights a history of backing significant companies, including the patient-intake platform Phreesia, which went public, and Current Health, which was acquired by Best Buy.
LRVHealth is an ideal match if you're a founder developing technology for healthcare, as they offer support across seed, early, and late stages. Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
- Investment stages: Seed, Early Stage Venture, Late Stage Venture
- Industries of focus: Health Care, Enterprise, Medical Device, Security
- Geographical presence: Boston, MA
- Founded: 2000
- Notable portfolio companies: Carevive, Current Health, Phreesia, GetWellNetwork
- Portfolio size: 88 investments
You can refer to their website here.
3. M25
M25 is a Chicago-based venture capital firm and one of the most active early-stage investors in the Midwest. They focus on funding startups headquartered across 14 states in the region, backing over 100 companies.
The firm invests across a wide range of industries, from enterprise software to consumer and fintech. Their portfolio includes their first unicorn, the insurtech company Kin Insurance, and successful exits like the acquisition of Pactsafe by Ironclad.
M25 is a great option for founders in the Midwest seeking their first institutional funding at the seed or early stages. Their broad industry focus makes them a potential partner for many different types of businesses.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture
Industries of focus: Consumer, Enterprise, FinTech, Enterprise Software
Geographical presence: Chicago, IL (invests across the Midwest)
Founded: 2015
Notable portfolio companies: Kin Insurance, Loop Returns, Branch, Pactsafe
Portfolio size: 176 investments
You can refer to their website here.
4. G20 Ventures
G20 Ventures is a Boston-based firm that provides capital to enterprise and consumer technology companies. They invest across multiple funding rounds, from seed to late-stage venture.
The firm has a track record of backing companies to successful exits, including cloud communications platform Fuze and desktop virtualization company Frame. Their portfolio also includes enterprise data-governance platform Congruity360, showing their interest in deep enterprise tech.
G20 Ventures is a strong potential partner for founders who need a flexible investor with experience across multiple funding stages. Their focus on both enterprise and consumer tech makes them a good fit for companies with strong technical foundations and clear market potential.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Late Stage Venture
Industries of focus: Enterprise, Consumer, Information Technology, Web3
Geographical presence: Boston, MA
Founded: 2013
Notable portfolio companies: Fuze, Napster, Frame, Mable, Congruity360
Portfolio size: 51 investments
You can refer to their website here.
5. Brick & Mortar Ventures
Brick & Mortar Ventures is a San Francisco-based firm that backs companies developing software and hardware for the architecture, engineering, and construction industries. They focus on technology that modernizes how the built world is designed, constructed, and maintained.
The firm has a clear focus on early-stage startups in the construction and real estate technology sectors, with a history of backing companies to major exits. A prime example is their investment in PlanGrid, a construction platform acquired by Autodesk for $875 million.
This firm is an excellent match for founders building technology to solve problems in construction, engineering, or facility management. Their deep industry expertise and track record make them a valuable partner for early-stage companies in this space.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture
Industries of focus: Construction, Architecture, Civil Engineering, Facility Management, Hardware, Software
Geographical presence: San Francisco, CA
Founded: 2015
Notable portfolio companies: PlanGrid, BuildingConnected, Fieldwire, HoloBuilder
Portfolio size: 83 investments
You can refer to their website here.
6. PJC
PJC is a Boston-based venture capital firm that has been investing since 2001. The firm backs early-stage companies, with a focus on enterprise software, consumer technology, and AI.
The firm has a strong track record of supporting companies to major exits, including the acquisition of smart-home company Nest by Google and the IPO for expense-management platform Expensify. This history of successful outcomes in both consumer and enterprise markets highlights their experience in scaling businesses.
PJC is a compelling option for founders aiming for a significant exit, whether through a strategic acquisition or by going public. Their investment flexibility from seed to later stages makes them a potential long-term partner for ambitious teams.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Late Stage Venture
Industries of focus: Enterprise, Consumer, AI, FinTech, InsurTech
Geographical presence: Boston, MA
Founded: 2001
Notable portfolio companies: Nest, Expensify, Nexamp, Evergage, Appcast
Portfolio size: 133 investments
You can refer to their website here.
7. Capital One Ventures
As the strategic investment arm of Capital One, this firm funds startups that are building the future of data, technology, and financial services. They operate as a corporate venture fund, looking for companies that align with the long-term direction of their parent institution.
Their impressive portfolio includes major successes like the data platform Snowflake and enterprise AI search company Glean. A key characteristic is their flexibility, investing across all funding rounds from seed to late-stage, which signals a commitment to supporting companies throughout their growth journey.
Capital One Ventures is a strong match for founders in fintech, B2B, or data infrastructure who are seeking more than just capital. A partnership can provide strategic value and access to opportunities within the broader Capital One ecosystem.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Convertible Note, Early Stage Venture, Late Stage Venture
Industries of focus: B2B, FinTech, Big Data, Cloud Infrastructure, Enterprise
Geographical presence: San Francisco, CA
Founded: 2014
Notable portfolio companies: Snowflake, Glean, Melio, Aqua Security
Portfolio size: 123 investments
You can refer to their website here.
8. Frontures
Frontures is a San Francisco-based venture capital firm that concentrates on providing pre-seed and seed funding. The firm primarily backs startups in the enterprise software, blockchain, and internet sectors.
Their portfolio shows an interest in companies with deep technical foundations, from Jacobi Robotics simplifying factory automation to Kanari AI building dialect-aware speech recognition. This indicates a preference for businesses solving complex problems with specialized technology.
This firm is a strong potential match for founders building technically ambitious products at the earliest stages. If your company is focused on enterprise software, AI, or blockchain with a clear technical advantage, Frontures may be a good fit.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Pre-seed
Industries of focus: Enterprise, Blockchain, Internet, AI
Geographical presence: San Francisco, CA
Founded: 2019
Notable portfolio companies: Jacobi Robotics, Kanari AI, 3DOS, Neuronix AI Labs
Portfolio size: 21 investments
You can refer to their website here.
9. Dell Technologies Capital
As the investment arm of Dell Technologies, this firm backs founders building enterprise and cloud infrastructure companies. They invest across a company's full lifecycle, from seed funding through later growth rounds.
The firm has a history of backing companies to major exits, including the acquisition of Adallom by Microsoft and the IPO of Arista Networks. This track record in both software and hardware signals their ability to identify strategically valuable technology.
Dell Technologies Capital is an ideal partner if you're building deep tech for the enterprise and are looking for a strategic investor. The connection to Dell can provide market insights and opportunities beyond just the capital invested.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Late Stage Venture
Industries of focus: Enterprise, Cloud Infrastructure, Software, Financial Services
Geographical presence: Palo Alto, CA
Founded: 2012
Notable portfolio companies: Adallom, Barefoot Networks, Arista Networks, BastionZero
Portfolio size: 280 investments
You can refer to their website here.
10. Sputnik ATX
Sputnik ATX is an Austin-based venture fund and accelerator that focuses on early-stage companies. They specifically back "maker-founders," signaling a preference for founders who are hands-on builders.
The firm invests across a wide variety of sectors, from enterprise software and IT management to consumer-facing industries like beauty and retail. Their portfolio includes the award-winning compliance platform Cognitive View and the AI-driven freight consolidator Kargoplex.
Sputnik ATX is a good fit for early-stage founders, particularly those in the Austin area, who are deeply involved in product development. Their accelerator model provides hands-on support for getting a company off the ground.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture
Industries of focus: Enterprise, IT Management, Retail, Mobile, Social
Geographical presence: Austin, TX
Founded: 2017
Notable portfolio companies: Cognitive View, Kargoplex, LAMIK
Portfolio size: 116 investments
You can refer to their website here.
11. Expansion Venture Capital
Expansion Venture Capital is a New York-based firm that provides funding and mentorship to companies from seed to later growth stages. Since 2010, they have built a broad portfolio across sectors like fintech, consumer, and enterprise software.
The firm is known for backing major consumer and fintech brands through to successful public-market exits, including the IPOs for Lemonade and Allbirds. Their portfolio also features high-profile unicorns like Carta and Turo, highlighting their ability to support companies to massive scale.
This firm is a strong choice for founders building companies with the potential for widespread consumer adoption or significant disruption in the fintech space. Their track record suggests they are skilled at guiding companies toward IPOs and other large-scale outcomes.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Late Stage Venture
Industries of focus: Consumer, Enterprise, FinTech, InsurTech, Real Estate
Geographical presence: New York, NY
Founded: 2010
Notable portfolio companies: Allbirds, Carta, ClassPass, Lemonade, Turo
Portfolio size: 128 investments
You can refer to their website here.
12. Tech Square Ventures
Based in Atlanta, Tech Square Ventures is a venture capital firm that invests in seed and early-stage companies. They focus on enterprise software, marketplace and platform businesses, and tech-enabled services.
The firm shows a preference for companies with strong early validation, such as Moth + Flame, whose VR training platform is used by the U.S. Air Force. Their portfolio also includes companies like Coros, which provided tracking technology for Moderna's COVID-19 vaccine distribution, signaling an interest in businesses with critical, large-scale applications.
Tech Square Ventures is a strong potential partner for early-stage founders, particularly in the Southeast, who are building enterprise or logistics technology. Their focus on companies with tangible market traction makes them a good fit for businesses that have already secured early customer or government contracts.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Convertible Note
Industries of focus: Enterprise, Marketplace, Logistics, IoT, Supply Chain Management
Geographical presence: Atlanta, GA
Founded: 2014
Notable portfolio companies: Saleo, Coros, Moth + Flame, Cloverly
Portfolio size: 126 investments
You can refer to their website here.
13. Zeno Partners
Zeno Partners, through its subsidiary Zeno Ventures, invests in technology companies from early to growth stages. Based in San Francisco, the firm supports businesses across both the consumer and enterprise markets.
The firm’s portfolio shows a focus on high-growth companies, including the autonomous-vehicle software company Applied Intuition, valued at $15 billion, and the fintech unicorn Mercury. Their investments range from deep enterprise tools like Activeloop to consumer platforms like AvantStay, signaling their comfort with different business models.
Zeno Partners is a good match for founders building ambitious technology companies with clear paths to market leadership. Their experience across multiple funding stages makes them a valuable partner for teams planning for long-term growth.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Seed, Early Stage Venture, Late Stage Venture
Industries of focus: Consumer, Enterprise, Finance, Financial Services
Geographical presence: San Francisco, CA
Founded: 2016
Notable portfolio companies: Applied Intuition, Mercury, AvantStay, BioRender
Portfolio size: 54 investments
You can refer to their website here.
14. Lumia Capital
Lumia Capital is an expansion-stage venture firm that partners with US and European companies aiming for international growth. Based in San Francisco, they provide capital to help businesses scale into new markets.
A key part of their strategy is helping companies expand into emerging markets, a focus that sets them apart. Their track record includes major exits like the acquisition of Careem by Uber and the IPO for PagerDuty, showing their ability to support companies to significant scale.
Lumia Capital is a great fit for founders who have established product-market fit and are ready to scale internationally. If your enterprise or fintech company is based in the US or Europe and has a clear plan for global expansion, they could be a valuable partner.
Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Investment stages: Early Stage Venture, Late Stage Venture, Expansion
Industries of focus: Enterprise, SaaS, FinTech, Emerging Markets
Geographical presence: San Francisco, CA (invests in US & Europe)
Founded: 2011
Notable portfolio companies: Careem, PagerDuty, Kabbage
Portfolio size: 52 investments
You can refer to their website here.
What This Tells Us About The VC Scene for Enterprise Companies
This list of investors shows that the funding environment for the enterprise sector is quite balanced. There is significant capital available for early-stage companies looking for their first checks, but also a strong contingent of firms that support businesses through later growth rounds. The presence of many multi-stage investors suggests a commitment to long-term partnerships.
Geographically, while you see concentrations in hubs like Boston and the Bay Area, there are active, prominent investors in other regions like the Midwest and the Southeast. For you as a founder, this means that strong enterprise companies can attract capital regardless of their location or funding stage. Once funding is secured, Rho’s integrated financial tools — including business banking, corporate cards, and automated bill pay — help startups manage and deploy capital efficiently.
Raise Confidently with Rho
Raising capital requires significant focus, and knowing which investors to approach saves you valuable time and effort. We hope this overview gives you a clear starting point for your outreach.
Once your round is closed, the work of managing that capital begins. If you’ve just raised, Rho can help you set up your financial stack in minutes.
Our platform integrates business banking, corporate cards, and automated bill pay to help you manage your new funding with clarity. This lets you focus on growing your business, not on your finances.
FAQs about Venture Capital Firms Focused on Enterprise
What are the top enterprise VC firms in New York?
New York has a strong ecosystem for enterprise startups. Firms like Expansion Venture Capital are based there, but many VCs invest nationally. Focus on finding a firm whose thesis aligns with your business, regardless of their specific location.
Are there many SaaS-focused venture capital firms in Europe?
Yes, Europe has a growing number of SaaS-focused VCs, with hubs in London, Berlin, and Paris. Firms like Lumia Capital, mentioned in our list, actively help US and European companies with international growth, showing cross-Atlantic interest.
How is a growth-stage VC different from an early-stage one?
Early-stage VCs focus on helping you find product-market fit and build your initial team. Growth-stage investors provide larger checks to scale your go-to-market strategy and expand into new markets once you have significant traction.
What should I look for in a software VC firm besides capital?
Look for a partner with deep industry expertise who can provide strategic guidance and access to their network. The right VC offers more than just money; they should be a resource for hiring, strategy, and future fundraising.
How can I manage my capital after raising from a VC?
Once your round is closed, managing the capital is your next challenge. Rho integrates business banking, corporate cards, and automated bill pay to help you deploy your new funding with clarity and control.