Top 8 Venture Capital Firms for Health Diagnostics Startups

If you're a founder in the Health Diagnostics space, preparing to raise capital means knowing which investors truly understand your field. Finding the right partner who gets the nuances of medtech, biotech, or life sciences can make all the difference.

To help you find the right investors, our team at Rho curated this overview of the top VC firms in the Health Diagnostics sector. We want to give you a direct look at the firms that could be a great fit for your company.

Just raised, or about to? Set up your financial stack with Rho in minutes. We provide business banking, corporate cards, and bill pay—all built for startup teams moving fast.

Which VC Firms in Health Diagnostics Are Right for Your Stage?

Whether your company is in its early days or preparing for an exit, connecting with the right investors is key. Here’s a quick look at VC firms in the Health Diagnostics space, organized by the stage at which they invest.

Pre-seed and Seed VC Firms in Health Diagnostics

This initial stage is for companies just starting out, often with an idea or prototype, who need capital to validate their concept and build a team. For founders looking for diagnostics seed stage VC firms, partners like SmartGateVC and Boutique Venture Partners focus on providing this crucial early support.

Early Stage VC Firms in Health Diagnostics

Early-stage funding, typically Series A and B, is for companies with proven traction that need to scale operations, expand their team, and grow market presence. Prominent early-stage healthcare venture capital firms that concentrate on this growth phase include Genoa Ventures and Catalyst Health Ventures.

Late Stage VC Firms in Health Diagnostics

Late-stage rounds are designed for established companies preparing for a major expansion, an acquisition, or an initial public offering (IPO). If your company has reached this maturity, life sciences venture capital firms such as Takeda Ventures and Broadview Ventures specialize in providing capital for these significant milestones.

Keep in mind that many healthcare VC firms invest across multiple stages, from seed to late-stage rounds, adapting their support as your company grows.

Here is our detailed look at the top VC firms specializing in Health Diagnostics. We've gathered key information on their investment stages, geographic focus, and what makes each firm a strong potential partner for your company.

1. Genoa Ventures

Genoa Ventures is a venture capital firm based in San Francisco that invests in early-stage life sciences companies. They focus on the intersection of biology and technology, backing founders who are building category-defining businesses.

The firm supports companies from seed to late-stage rounds, with a clear focus on deep tech in biotech and health diagnostics. Their portfolio includes notable exits like the IPO of Caribou Biosciences and the acquisition of Zymergen, showing their ability to guide companies to major milestones.

Genoa Ventures is a strong match for founders with deep scientific expertise in complex fields like genomics, bioinformatics, and bio-manufacturing. If your startup needs a partner with technical depth and a track record of successful exits, this firm is worth a look.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: Life Science, Biotechnology, Health Diagnostics, Genetics, and Bioinformatics
• Geographical presence: San Francisco, California
• Founded: 2014
• Notable portfolio companies: Caribou Biosciences, Zymergen, Mission Bio
• Portfolio size: 35 investments

You can refer to their website here.

2. SmartGateVC

SmartGateVC is a pre-seed and seed-stage venture capital firm with offices in Southern California and Armenia. They invest in companies working on complex challenges where artificial intelligence intersects with fields like life sciences.

The firm concentrates on deep-tech startups, particularly those applying AI to bioinformatics, medical devices, and health diagnostics. Their portfolio includes companies like SuperAnnotate and Krisp, which have gained significant industry recognition and awards.

SmartGateVC is a good match for founders at the earliest stages who are building AI-native companies in highly technical sectors. If your startup is using AI to solve fundamental problems, this firm could be a strong partner.

• Investment stages: Seed, early-stage venture
• Industries of focus: Artificial Intelligence, Bioinformatics, Health Diagnostics, Medical Devices, Cyber Security
• Geographical presence: Southern California and Armenia
• Founded: 2017
• Notable portfolio companies: SuperAnnotate, Krisp, Deep Origin, Britive
• Portfolio size: 28 investments

You can refer to their website here.

3. Catalyst Health Ventures

Catalyst Health Ventures is a Boston-based firm that funds companies creating new solutions for significant unmet needs in healthcare. They invest across various stages, from seed to late-stage, supporting companies throughout their growth.

The firm has a strong record in the medical device and health diagnostics sectors, with notable exits like the acquisition of Augmenix by Boston Scientific and the IPO of Sera Prognostics. This history shows their ability to back companies with strong clinical and commercial potential, guiding them toward successful outcomes.

CHV is a great potential partner for founders developing tangible products in the medical device or diagnostics space that address clear clinical gaps. If your company has a well-defined solution for a pressing healthcare problem, their focused expertise could be a valuable asset.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: Health Care, Health Diagnostics, Medical Device
• Geographical presence: Boston, Massachusetts
• Founded: 2008
• Notable portfolio companies: Augmenix, Sera Prognostics, Kaleidoscope Innovation
• Portfolio size: 46 investments

You can refer to their website here.

4. StartUp Health

StartUp Health is a New York-based venture firm with a global mission to back founders aiming for major breakthroughs in healthcare. They invest broadly across the health sector, including diagnostics, biotech, and digital health.

The firm’s most distinct feature is its massive portfolio and community-driven approach, aiming to build a "global army" of entrepreneurs. Their portfolio includes high-profile companies like women's health platform Tia and the diabetes-management startup Bigfoot Biomedical.

This firm is a strong fit for founders with ambitious, long-term goals—what they call "health moonshots"—who value being part of a large, active community. If you're building a company in any sub-sector of healthcare and want a partner with a vast network, StartUp Health is a compelling choice.

• Investment stages: Seed, early-stage venture, and grants
• Industries of focus: Health Care, Health Diagnostics, Biotechnology, Medical Device, mHealth, Personal Health
• Geographical presence: New York, New York
• Founded: 2011
• Notable portfolio companies: Tia, Bigfoot Biomedical, Cyclica, Human API
• Portfolio size: 390 investments

You can refer to their website here.

5. Broadview Ventures

Broadview Ventures is a Boston-based firm dedicated to advancing technologies that treat cardiovascular and neurovascular diseases. They support companies across their entire lifecycle, from initial seed funding to later-stage growth and private equity rounds.

What makes Broadview different is its singular focus on heart and brain health, allowing the team to offer deep subject-matter expertise. Their portfolio demonstrates a track record of guiding companies to key commercial milestones, including the IPO of Lyra Therapeutics and the launch of Ischemia Care’s diagnostic test for stroke.

This firm is an ideal partner for founders developing specialized medical devices, diagnostics, or therapeutics within the cardiovascular or neurovascular fields. If your company is tackling these specific health challenges, Broadview’s focused approach could provide critical support.

• Investment stages: Seed, early-stage, late-stage venture, and private equity
• Industries of focus: Health Diagnostics, Life Science, Medical Device, Therapeutics
• Geographical presence: Boston, Massachusetts
• Founded: 2008
• Notable portfolio companies: Lyra Therapeutics, Ischemia Care, Cardiosense
• Portfolio size: 74 investments

You can refer to their website here.

6. Leap Venture Studio

Leap Venture Studio is a Los Angeles-based accelerator that backs early-stage companies creating new products and services for the pet care market. They partner with founders to accelerate growth and innovation across the entire pet ecosystem.

The firm's exclusive focus on the pet industry allows them to provide specialized support, with a portfolio that includes pet health diagnostics company AnimalBiome and plant-based pet food brand Wild Earth. As a venture studio and accelerator, their model is built to provide hands-on guidance to companies at their earliest stages.

Leap Venture Studio is an excellent match for founders developing products in pet health, nutrition, or services who are seeking seed or early-stage funding. If you're looking for a partner with deep industry connections and a structured program to help scale your pet-focused company, this firm is a strong contender.

• Investment stages: Seed, Early-stage venture
• Industries of focus: Pet, Health Diagnostics, Nutrition, Veterinary, Service Industry
• Geographical presence: Los Angeles, California
• Founded: 2018
• Notable portfolio companies: AnimalBiome, Wild Earth, Smalls, BorrowMyDoggy
• Portfolio size: 43 investments

You can refer to their website here.

7. Boutique Venture Partners

Boutique Venture Partners is a Palo Alto-based firm that provides seed and early-stage funding to companies in healthcare and life sciences. They focus on startups working on complex challenges in areas like therapeutics, medical devices, and biotechnology.

The firm's portfolio highlights a focus on companies with strong scientific foundations and clear paths to commercialization, such as miRecule's partnership with Sanofi. They back startups across a range of technical fields, including 3D printing, genetics, and therapeutics, often with strong corporate interest like Mitra Chem's investment from General Motors.

Boutique Venture Partners is a good fit for founders with a deep-tech background in healthcare who are seeking early-stage capital. If your company has a strong scientific or technical advantage that can attract major industry partners, this firm could be a valuable investor.

• Investment stages: Seed, early-stage venture
• Industries of focus: Health Care, Life Science, Health Diagnostics, Medical Devices, Therapeutics, Biotechnology
• Geographical presence: Palo Alto, California
• Founded: 2020
• Notable portfolio companies: miRecule, Mitra Chem, Zeda, Genalyte
• Portfolio size: 24 investments

You can refer to their website here.

8. Takeda Ventures

Takeda Ventures is the corporate venture capital arm of the global pharmaceutical company, Takeda. Based in San Diego, they invest worldwide in high-potential companies developing new therapeutics and platform technologies.

As a corporate VC, the firm offers more than just capital, providing access to deep industry expertise and the resources of a major pharma organization. Their portfolio is marked by significant successes, including IPOs for companies like Avidity Biosciences and major collaboration deals for startups like Obsidian Therapeutics.

This firm is a strong match for founders whose companies are focused on therapeutics or platform technologies with clear clinical pathways. If your startup could benefit from a strategic partnership with an established industry leader, Takeda Ventures is an excellent potential investor.

• Investment stages: Early-stage and late-stage venture
• Industries of focus: Therapeutics, Health Diagnostics, Life Science Platforms
• Geographical presence: San Diego, California
• Founded: 2001
• Notable portfolio companies: NGM Biopharmaceuticals, Avidity Biosciences, Be Biopharma, Obsidian Therapeutics
• Portfolio size: 98 investments

You can refer to their website here.

What This Tells Us About The VC Scene for Health Diagnostics Companies

Our review of these firms shows that the Health Diagnostics sector has a diverse and active funding environment. You'll find strong support at the early stages, with many firms dedicated to seed and Series A rounds. However, there are also established partners for later-stage growth, indicating a healthy pipeline for companies as they mature.

Geographically, investors are concentrated in major biotech hubs like Boston and California, which can be a key consideration for your fundraising strategy. The variety of firms—from corporate VCs to those with a narrow focus on specific diseases or markets—means you can find a partner whose expertise truly aligns with your company's goals. The investor base appears well-balanced, offering opportunities for a wide range of founders.

Raise Confidently with Rho

Knowing which investors to approach saves valuable time and energy during a fundraise. We created this overview to help you find partners who truly understand your work in Health Diagnostics.

Once your round is closed, the work of managing that capital begins. If you’ve just raised, Rho can help you set up your financial stack in minutes.

Our platform gives you the tools to manage your new funding efficiently, with business banking, corporate cards, and bill pay solutions built for startups.

FAQs about Venture Capital Firms Focused on Health Diagnostics

Which healthcare venture capital firms in NYC focus on diagnostics?

New York is a major hub for health tech investors. Firms like StartUp Health are based there, and many generalist healthcare VCs in the city actively invest in promising diagnostics companies with strong founding teams and clear market potential.

Are there European healthcare venture capital firms investing in diagnostics?

Yes, many European VCs specialize in life sciences and diagnostics. They often seek companies with a clear regulatory strategy for the EMA and an approach that can scale across multiple European markets, offering a significant international growth opportunity.

What do early-stage diagnostics VC firms look for?

Early-stage investors prioritize a strong founding team with deep domain expertise. They also look for a solid scientific foundation, a clear clinical need for your technology, and initial data that validates your approach and market opportunity.

What is the difference between corporate and traditional medical venture capital firms?

Traditional VCs primarily seek financial returns. Corporate VCs, like Takeda Ventures, also look for strategic alignment with their parent company’s goals, offering industry access and potential partnerships in addition to capital for your startup.

How can Rho help after I secure funding?

Once your round is closed, our platform helps you manage your new capital with integrated business banking, corporate cards, and automated bill pay. You can get started with Rho in just a few minutes.