Top 8 Venture Capital Firms for Health Diagnostics Startups

As a founder in the Health Diagnostics space, you know that securing capital is about more than just the money—it’s about finding a partner who understands your specific field. Whether you're in medtech, life sciences, or biotech, the right investor can make all the difference.

To help you find that fit, our team has curated this overview of top venture capital firms active in Health Diagnostics. Use this guide to identify investors who are genuinely focused on your industry before you begin your raise.

Rho provides access to business banking, corporate cards, and bill pay — built for startup teams moving fast.

Key Takeaways

• For a Health Diagnostics startup, securing venture funding is more than a financial transaction; it’s a validation of your science and a partnership that provides the resources needed for long-term development and regulatory milestones.
• Firms like Genoa Ventures, SmartGateVC, Catalyst Health Ventures, and StartUp Health are notable backers in the Health Diagnostics field, each with a history of supporting companies in this specialized area.
• Once you secure funding, our integrated platform helps you manage and deploy that capital efficiently with business banking, corporate cards, and automated bill pay.

Which VC Firms in Health Diagnostics Are Right for Your Stage?

Whether your company is in its early stages or preparing for an exit, knowing the right investors to approach makes all the difference. To help, we’ve created a quick overview of VC firms in Health Diagnostics, organized by the stages they invest in.

Pre-seed and Seed VC Firms in Health Diagnostics

Pre-seed and seed funding are the earliest forms of capital, typically used to validate your initial concept, build a prototype, and assemble a founding team. For diagnostics startups at this initial phase, firms like SmartGateVC and Boutique Venture Partners are active seed stage healthcare venture capital firms to consider.

Early Stage VC Firms in Health Diagnostics

Early-stage funding, which includes Series A and B rounds, is meant to help you achieve product-market fit, scale commercial operations, and expand your team. Among the many early stage biotech venture capital firms, Genoa Ventures and the Boston-based Catalyst Health Ventures have strong track records in this area.

Late Stage VC Firms in Health Diagnostics

Late-stage capital is for established companies looking to scale aggressively, expand into new markets, or prepare for an exit through an acquisition or IPO. If your company has reached this point, medical device venture capital firms like Takeda Ventures and Broadview Ventures specialize in providing growth capital to mature businesses.

Keep in mind that some versatile life sciences venture capital firms, such as StartUp Health, invest across multiple stages. Once you secure funding, Rho’s integrated platform helps you manage and deploy that capital efficiently with business banking, corporate cards, and automated bill pay.

To help you identify the right partners, we've compiled more information on the top VC firms active in the Health Diagnostics field. The following section covers their investment stages, geographic focus, and what makes each firm a compelling choice for founders.

1. Genoa Ventures

Based in San Francisco, Genoa Ventures is a firm that invests in early-stage life science companies where biology meets technology. They focus on startups innovating in areas like bioinformatics, genetics, and health diagnostics.

A distinguishing feature is their portfolio's track record of significant outcomes, including the IPO of Caribou Biosciences and the acquisition of Zymergen, another notable portfolio company. This demonstrates their ability to back companies from the early stages through to major exits.

This firm is an excellent match for founders with deep scientific expertise who are building companies at the seed or early stages. If your work is in genomics, bio-manufacturing, or diagnostics, their focused approach could be a strong fit.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: Life Science, Biotechnology, Health Diagnostics, Bioinformatics, Genetics
• Geographical presence: San Francisco, California
• Founded: 2014
• Notable portfolio companies: Caribou Biosciences, Zymergen, Mission Bio, NanoCellect Biomedical
• Portfolio size: 35 investments

You can refer to their website here.

2. SmartGateVC

SmartGateVC is a pre-seed and seed-stage venture firm with offices in Southern California and Armenia. They back founders building companies at the intersection of deep tech and artificial intelligence.

The firm concentrates on AI-powered solutions in complex fields like health diagnostics, bioinformatics, and cybersecurity. Their portfolio includes companies like Krisp, an AI noise-cancellation app named to TIME’s Best Inventions, and Britive, a cloud security startup that recently closed a $20.5 million Series B.

This firm is a good fit for founders at the pre-seed or seed stage whose work is grounded in artificial intelligence. If your startup is applying AI to solve problems in health, security, or human-computer interaction, SmartGateVC’s focus aligns well.

• Investment stages: Seed, early-stage venture
• Industries of focus: Artificial Intelligence (AI), Bioinformatics, Health Diagnostics, Medical Device, Cyber Security
• Geographical presence: Los Angeles, California and Armenia
• Founded: 2017
• Notable portfolio companies: Krisp, SuperAnnotate, Deep Origin, Britive
• Portfolio size: 28 investments

You can refer to their website here.

3. Catalyst Health Ventures

Catalyst Health Ventures is a Boston-based firm that invests in companies creating solutions for unmet healthcare needs. They support businesses from seed to late stages, focusing on the medical device and health diagnostics sectors.

The firm has a history of backing companies to major outcomes, including the acquisition of Augmenix by Boston Scientific and the IPO of Sera Prognostics. This signals their ability to guide companies from early development through to significant market success.

This firm is a strong match for founders developing tangible products in the medical device or diagnostics space. If you have a clear solution for a specific clinical problem, their focus and track record could be a valuable asset.

• Investment stages: Seed, early-stage, and late-stage venture
• Industries of focus: Health Care, Health Diagnostics, Medical Device
• Geographical presence: Boston, Massachusetts
• Founded: 2008
• Notable portfolio companies: Augmenix, Sera Prognostics, Kaleidoscope Innovation
• Portfolio size: 46 investments

You can refer to their website here.

4. StartUp Health

StartUp Health is a New York-based firm that invests in what it calls a "global army of Health Transformers" to solve major health challenges. They support a wide range of companies across the healthcare spectrum, from biotechnology and medical devices to digital health and diagnostics.

A key aspect of StartUp Health is its wide investment mandate, backing companies from seed to later venture rounds across more than ten health-related industries. Their portfolio includes significant exits like the AI drug-discovery company Cyclica and commercially advanced firms like Bigfoot Biomedical.

This firm is a great fit for mission-driven founders with ambitious goals, or "health moonshots," as the firm calls them. If your company operates anywhere within the health-tech ecosystem and you value a partner with a large, diverse network, StartUp Health is worth considering.

• Investment stages: Seed, early-stage venture, and grants
• Industries of focus: Biotechnology, Health Care, Health Diagnostics, Medical Device, Personal Health
• Geographical presence: New York, New York
• Founded: 2011
• Notable portfolio companies: Cyclica, Bigfoot Biomedical, Tia, MetaLogics Corporation
• Portfolio size: 390 investments

You can refer to their website here.

5. Broadview Ventures

Broadview Ventures is a Boston-based firm that funds companies developing technology for cardiovascular and neurovascular diseases. They support businesses across the full company lifecycle, from seed rounds to private equity investments.

The firm has a distinct focus on its target disease areas and a portfolio that shows a path to significant outcomes. Notable portfolio companies include Lyra Therapeutics, which had a successful IPO, and Ischemia Care, which has brought its diagnostic blood test to market.

This firm is a strong match for founders with deep technical expertise in the cardiovascular or neurovascular space. If your company is creating a medical device, diagnostic tool, or therapeutic in this field, Broadview’s specialized focus could be a valuable asset.

• Investment stages: Seed, early-stage, late-stage venture, and private equity
• Industries of focus: Cardiovascular and neurovascular diseases, Health Diagnostics, Life Science, Medical Device, Therapeutics
• Geographical presence: Boston, Massachusetts
• Founded: 2008
• Notable portfolio companies: Lyra Therapeutics, Ischemia Care, Cardiosense
• Portfolio size: 74 investments

You can refer to their website here.

6. Leap Venture Studio

Leap Venture Studio is a Los Angeles-based accelerator focused on early-stage companies in the pet care industry. They partner with founders to advance new ideas in the growing pet ecosystem.

The firm operates as an accelerator, providing hands-on support to seed and early-stage ventures in pet-related fields. Their portfolio includes companies like Wild Earth, a plant-based pet food brand that appeared on Shark Tank, and AnimalBiome, a leader in pet microbiome testing.

This accelerator is a great match for founders at the seed or early stages who are building companies in the pet care market. If your work involves pet health diagnostics, nutrition, or veterinary services, their specialized program could provide the right support.

• Investment stages: Seed, early-stage venture
• Industries of focus: Pet Care, Health Diagnostics, Nutrition, Veterinary
• Geographical presence: Los Angeles, California
• Founded: 2018
• Notable portfolio companies: Wild Earth, AnimalBiome, Smalls, Barkibu
• Portfolio size: 43 investments

You can refer to their website here.

7. Boutique Venture Partners

Boutique Venture Partners is a Palo Alto-based firm that provides capital to seed and early-stage companies in healthcare and life sciences. They support founders working on new technologies across a range of medical fields.

The firm backs companies with deep technical foundations, and its portfolio includes ventures with major strategic partners like Sanofi and General Motors. Their investments often involve platform technologies, from AI-driven battery development to 3D-printed medical devices.

This firm is a good match for founders at the seed or early stages who are building platform technologies with broad applications. If your company is grounded in deep science, whether in therapeutics, diagnostics, or advanced manufacturing, their approach may be a strong fit.

• Investment stages: Seed, early-stage venture
• Industries of focus: Health Care, Life Science, Health Diagnostics, Medical Device, Biotechnology
• Geographical presence: Palo Alto, California
• Founded: 2020
• Notable portfolio companies: miRecule, Mitra Chem, Zeda, Genalyte
• Portfolio size: 24 investments

You can refer to their website here.

8. Takeda Ventures

Takeda Ventures is the corporate venture capital arm of Takeda Pharmaceutical, focusing on high-caliber therapeutic and platform-based opportunities around the world. They support companies across both early and late venture stages.

As a corporate VC, the firm seeks strategic alignment and has a portfolio marked by major outcomes, including the IPOs of NGM Biopharmaceuticals and Avidity Biosciences. This highlights their ability to guide companies to significant exits.

This firm is a strong match for founders developing platform technologies or therapeutics who are open to the resources of a major pharmaceutical partner. Their focus is on companies that have already found some traction and are in the venture stages.

• Investment stages: Early-stage and late-stage venture
• Industries of focus: Therapeutics, Health Diagnostics, Finance, Financial Services
• Geographical presence: San Diego, California (invests globally)
• Founded: 2001
• Notable portfolio companies: NGM Biopharmaceuticals, Avidity Biosciences, Be Biopharma, Obsidian Therapeutics
• Portfolio size: 98 investments

You can refer to their website here.

What This Tells Us About The VC Scene for Health Diagnostics Companies

This overview shows a healthy funding environment for companies in health diagnostics. There is significant capital available for early-stage founders, with several firms concentrating on pre-seed and seed rounds. At the same time, many investors on this list support companies across multiple stages, from initial funding to later growth rounds. This indicates that you can find partners for both getting started and for long-term scaling.

Geographically, investment activity is concentrated in established life science centers like Boston and California. The variety of investors is also notable, ranging from traditional venture firms and accelerators to corporate VC arms. This gives you different types of potential partners to consider, depending on your company's needs. Once you secure funding, Rho’s integrated financial tools—including business banking, corporate cards, and automated bill pay—help you manage and deploy that capital efficiently.

Raise Confidently with Rho

A fundraise demands your full attention, and a focused list of relevant investors saves you valuable time. We created this guide to give you a clear starting point for your outreach.

When you secure funding, the next step is putting that capital to work efficiently. Rho can help you set up your financial stack in minutes.

Our platform combines business banking, corporate cards, and automated bill pay to help you manage your new funds. This gives you the financial control needed to grow your company.

FAQs about Venture Capital Firms Focused on Health Diagnostics

Which healthcare venture capital firms are in NYC?

New York is a major hub for health tech investment. Firms like StartUp Health are based there, and many other VCs have a presence, making it a strong city for founders seeking capital for their health diagnostics company.

Are there European venture capital firms for diagnostics startups?

Yes, Europe has a growing number of VCs focused on health tech and diagnostics. Firms often specialize in life sciences and medtech, providing capital for companies looking to scale within the European market and beyond.

How do I find early-stage healthcare venture capital firms?

Focus on firms that explicitly state an early-stage investment thesis. Review the portfolios of VCs like Genoa Ventures to confirm they back companies at your stage. Once funded, our platform helps you manage that capital with integrated financial tools.

What do medical device VC firms look for?

Medical device VCs prioritize companies with strong intellectual property, a clear regulatory strategy, and a solution for a significant unmet clinical need. A working prototype and early data are often essential for securing their interest.

What should I do after securing funding?

Once you secure funding, it's critical to manage it well. Rho helps you set up your financial operations quickly, offering integrated business banking, corporate cards, and automated payments to deploy your capital effectively.