Top 15 Venture Capital Firms Investing in Healthcare

For founders in the Healthcare sector, identifying the right investors is a critical part of preparing to raise capital. Understanding which venture capital firms specialize in your area—whether it's HealthTech, Life Sciences, Biotech, or MedTech—can make your fundraising process more effective.

To assist with your research, our team has curated this guide to some of the top VC firms investing in healthcare. We hope this overview helps you quickly find investors who are a good fit for your company.

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Which VC Firms in Healthcare Are Right for Your Stage?

Whether you're an early-stage company or preparing for an exit, knowing who to talk to makes a difference. Here’s a quick look at which healthcare VC firms invest at each stage.

Pre-seed and Seed VC Firms in Healthcare

Pre-seed and seed funding are the earliest forms of capital, typically used to validate an idea and build a minimum viable product. Some health and wellness venture capital firms focusing on this stage include New York-based Springbank Collective and TMV, along with the incubator and VC 25madison.

Early Stage VC Firms in Healthcare

Early-stage funding, which includes Series A and B rounds, helps companies with a proven product to scale their operations and market presence. Among the many early-stage healthcare venture capital firms, you might look into Third Rock Ventures, a key player among biotech venture capital firms in Boston, or connect with LRVHealth and Maverick Ventures.

Late Stage VC Firms in Healthcare

Late-stage capital is for established companies looking to expand significantly, prepare for an IPO, or position themselves for acquisition. Notable late stage venture capital firms in the Bay Area and New York include New Enterprise Associates, Vivo Capital, and Deerfield Management.

Keep in mind that some VC firms invest across all startup funding stages, from the earliest rounds through to a company's growth and exit phases.

To help you identify the right partners, here is a closer look at some of the top VC firms in healthcare. We've outlined their investment stages, geographic focus, and what makes each a distinct choice for founders.

1. Deerfield Management

Based in New York, Deerfield Management is a healthcare investment firm that extends its work beyond capital into information and philanthropy. Since its founding in 1994, the firm has supported companies across the healthcare spectrum.

A key aspect of their model is investing across a company's entire lifecycle, from seed funding to post-IPO stages. Their portfolio includes major public companies like the managed-care insurer Centene Corporation and biotechs they've backed through an IPO like Nuvalent.

Deerfield may be a good match if you are a healthcare founder seeking a long-term financial partner that can support your company through various growth phases. Their focus on biotech, pharmaceuticals, and health insurance makes them particularly relevant for companies in those areas.

• Investment stages: Seed, early stage, late stage, and post-IPO
• Industries of focus: Health Care, Health Insurance, Information Services
• Geographical presence: New York, NY
• Founded: 1994
• Notable investments: Nuvalent, Viatris, and Neurocrine Biosciences

You can refer to their website here.

2. Silversmith Capital Partners

Based in Boston, Silversmith Capital Partners is a growth equity firm that invests in technology and healthcare companies. They focus on partnering with profitable, founder-led businesses to help them accelerate growth.

Silversmith's approach centers on capital-efficient companies that have already found product-market fit. Their portfolio includes well-known SaaS companies like ActiveCampaign and Webflow, demonstrating their expertise in scaling software businesses.

This firm may be a good match if you are a founder of a bootstrapped or profitable company in tech or healthcare IT. They are well-suited for entrepreneurs seeking a hands-on partner for the next stage of growth, rather than early-stage venture funding.

• Investment stages: Seed, early stage, late stage, and private equity
• Industries of focus: Healthcare, Information Technology, Information Services
• Geographical presence: Boston, MA
• Founded: 2015
• Notable investments: ActiveCampaign, Webflow, and SurveyMonkey (Momentive)
• Portfolio size: 54 investments

You can refer to their website here.

3. New Enterprise Associates

New Enterprise Associates (NEA) is one of the most established venture capital firms, investing in both technology and healthcare since 1977. Their extensive history gives them a deep well of experience across various market cycles and technology shifts.

A key feature of NEA's model is its ability to invest across the full company lifecycle, from early rounds to post-IPO. This flexibility is shown in their backing of companies like the AI platform Databricks and the oncology drug developer Tesaro.

The firm is a strong choice for founders in tech or healthcare who want a long-term partner capable of providing capital and support at every stage. Their track record in biotech and enterprise software makes them particularly relevant for companies in those sectors.

• Investment stages: Early stage, late stage, post-IPO, and venture
• Industries of focus: Technology and Healthcare
• Geographical presence: Menlo Park, CA
• Founded: 1977
• Notable investments: Databricks, 3Com, and Tesaro
• Portfolio size: Over 2,200 investments

You can refer to their website here.

4. Vivo Capital

Vivo Capital is a global investment firm dedicated to the healthcare sector, managing approximately $5.8 billion in assets. They operate from their base in Palo Alto and focus on supporting healthcare innovation worldwide.

The firm invests across the entire company lifecycle, from early venture stages to post-IPO and private equity. Their portfolio, detailed in public filings, shows a strong emphasis on life sciences companies with late-stage clinical assets like Soleno Therapeutics and Verona Pharma, both with therapies advancing through FDA review.

Vivo Capital is an ideal partner if you are a founder in the biotech or pharmaceutical space, particularly if your company is approaching or in clinical trials. Their multi-stage investment capability makes them a good fit for founders seeking a long-term financial partner to guide them from development to commercialization.

• Investment stages: Early stage, late stage, post-IPO, private equity, and venture
• Industries of focus: Health Care
• Geographical presence: Palo Alto, CA
• Founded: 1996
• Notable investments: Geron Corporation, Avadel Pharmaceuticals, and Trevi Therapeutics
• Portfolio size: 224 investments

You can refer to their website here.

5. Maverick Ventures

As the venture arm of Maverick Capital, Maverick Ventures invests in early-stage healthcare and technology-driven businesses from its base in San Francisco. They support founders building companies at the intersection of these two dynamic sectors.

The firm has a strong track record of guiding companies to significant outcomes, such as the One Medical acquisition by Amazon and the public offering for Hims & Hers. This history demonstrates their ability to support founders from the early stages through to major M&A and IPO events.

Maverick Ventures is a compelling choice for founders in health tech or enterprise software who are looking for a long-term partner. If your goal is to build a category-defining company, their experience with high-growth trajectories could be a valuable asset.

• Investment stages: Seed, early stage, late stage, and venture
• Industries of focus: Health Care, Cyber Security, Generative AI
• Geographical presence: San Francisco, CA
• Founded: 2015
• Notable investments: Coupang, One Medical, Hims & Hers, and Cityblock Health
• Portfolio size: 199 investments

You can refer to their website here.

6. SV Health Investors

SV Health Investors is a Boston-based firm that has been funding companies in the biotechnology and healthcare sectors since 1993. They manage a diverse portfolio, investing across the full spectrum of healthcare innovation.

The firm's model is defined by its ability to support companies at every stage, from seed funding through to post-IPO and private equity. Their portfolio highlights significant exits, including the ~$1 billion acquisition of Achillion Pharmaceuticals and the IPO of telehealth leader Amwell, which is noted on their portfolio page.

SV Health Investors is a strong potential partner if you are a founder in biotech, life sciences, or medical devices. Their long-term, multi-stage approach is well-suited for companies seeking a partner for their entire growth journey, from initial research to commercial success.

• Investment stages: Seed, early stage, late stage, post-IPO, private equity, and debt
• Industries of focus: Biotechnology, Health Care, Life Science, Medical Device
• Geographical presence: Boston, MA
• Founded: 1993
• Notable investments: American Well (Amwell), Insulet Corporation, and Achillion Pharmaceuticals
• Portfolio size: 317 investments

You can refer to their website here.

7. Versant Ventures

Versant Ventures, founded in 1999, is a healthcare-focused investment firm based in Menlo Park. They support companies across multiple financing stages, from early venture rounds to post-IPO and private equity.

The firm is known for backing companies built on groundbreaking science, guiding them from early stages to major public offerings or acquisitions. Their portfolio includes foundational companies like CRISPR Therapeutics, which they supported from its Series A, and Audentes Therapeutics, which was acquired for $3 billion.

Versant may be a good fit if you are a founder in the life sciences or biotech space with a company built on a strong scientific discovery. They are well-equipped to partner with teams that have ambitions for significant, long-term growth and an eventual IPO or major acquisition.

• Investment stages: Early stage, late stage, post-IPO, private equity, and debt
• Industries of focus: Health Care
• Geographical presence: Menlo Park, CA
• Founded: 1999
• Notable investments: CRISPR Therapeutics, Jazz Pharmaceuticals, Inari Medical, and RayzeBio
• Portfolio size: 383 investments

You can refer to their website here.

8. Pfizer

Pfizer is a major biopharmaceutical company that also operates as a corporate venture capital investor. With roots dating back to 1849, the New York-based firm uses its venture arm to fund innovative companies across the healthcare sector.

Pfizer Ventures focuses on companies with strong scientific foundations, particularly in biotechnology and pharmaceuticals. Their portfolio includes companies like Arrakis Therapeutics, which is developing RNA-targeted drugs, and Artios Pharma, a leader in DNA-damage-response oncology, signaling a clear interest in pioneering therapeutic approaches.

This firm is a strong choice for founders in the biotech and pharmaceutical fields whose work aligns with Pfizer's strategic interests. If you are seeking a partner that offers both capital and the potential for deep collaboration with a global industry leader, Pfizer Ventures could be a valuable connection.

• Investment stages: Private equity and venture
• Industries of focus: Biotechnology, Health Care, Medical, Pharmaceutical, Precision Medicine
• Geographical presence: New York, NY
• Founded: 1849
• Notable investments: Arrakis Therapeutics, Artios Pharma, Rhythm Pharmaceuticals, Medtronic
• Portfolio size: 52 investments

You can refer to their website here.

9. Redmile Group

Redmile Group is a San Francisco-based investment firm focused exclusively on the healthcare sector. They operate across a wide spectrum of financing, from venture and growth rounds to public market investments.

A key feature of Redmile's strategy is its crossover model, investing in both private and public healthcare companies. This is evident in their portfolio, which includes companies like the COVID-19 vaccine developer BioNTech and the digital health unicorn Virta Health.

Redmile Group may be a good fit if you are a founder of a healthcare company with significant growth potential, regardless of your current stage. Their ability to provide capital from early venture stages through to post-IPO makes them a suitable partner for teams seeking long-term financial backing.

• Investment stages: Early stage, late stage, post-IPO, and private equity
• Industries of focus: Health Care
• Geographical presence: San Francisco, CA
• Founded: 2007
• Notable investments: BioNTech, Virta Health, and Science 37
• Portfolio size: 189 investments

You can refer to their website here.

10. 25madison

Based in New York, 25madison is a venture platform that functions as both an incubator and an early-stage investor. They build companies from the idea stage and also fund existing startups to accelerate their growth.

A key feature of their model is this hybrid approach, which combines company building with traditional venture investing. Their diverse portfolio includes the public safety app Citizen and the avatar-technology unicorn Genies, showing their ability to back companies across consumer and tech sectors.

This firm is a strong option if you are an early-stage founder in consumer tech, fintech, or healthcare seeking hands-on support. Their incubator model is especially fitting for entrepreneurs who want a partner to help build and launch a business from the ground up.

• Investment stages: Seed, early stage, and venture
• Industries of focus: Health Care, FinTech, Consumer Software
• Geographical presence: New York, NY
• Founded: 2018
• Notable investments: Citizen, Genies, Hut 8, Landa
• Portfolio size: 57 investments
• Investor type: Incubator and venture capital firm

You can refer to their website here.

11. LRVHealth

LRVHealth is a Boston-based venture capital firm that has operated as an “Inside Healthcare” platform since 2000. Their team is composed of experienced healthcare investors, operators, and advisors who bring deep industry knowledge to their partnerships.

The firm’s model emphasizes hands-on support, leveraging its operational background to guide companies. This is reflected in their portfolio, which includes successful exits like the patient-monitoring startup Current Health and the patient-intake platform Phreesia, which had a successful IPO.

LRVHealth is a strong choice for founders in health tech who value a partner with direct operational experience. If you are building a company in areas like patient engagement or data interoperability and seek more than just capital, their team could be a key resource.

• Investment stages: Seed, early stage, and late stage venture
• Industries of focus: Health Care, Medical Device, Enterprise
• Geographical presence: Boston, MA
• Founded: 2000
• Notable investments: Phreesia, Current Health, Carevive, GetWellNetwork
• Portfolio size: 88 investments

You can refer to their website here.

12. Third Rock Ventures

Third Rock Ventures is a Boston-based firm that builds and invests in life science companies with the potential for significant impact. They focus on backing businesses that are developing new approaches in biotechnology and medicine.

The firm is known for its hands-on approach, often building companies from the ground up around major scientific breakthroughs. Their portfolio includes pioneers like the gene-editing company Editas Medicine and Sage Therapeutics, which developed the first FDA-approved therapy for postpartum depression, both becoming high-profile successes for the firm.

Third Rock is an ideal partner for founders with a strong scientific background who are tackling complex challenges in life sciences. If your company is built on a foundational discovery in areas like gene therapy or oncology, their model of deep engagement could be a great fit.

• Investment stages: Seed, early stage, late stage, and post-IPO
• Industries of focus: Biotechnology, Health Care, Medical Device
• Geographical presence: Boston, MA
• Founded: 2007
• Notable investments: Sage Therapeutics, Editas Medicine, bluebird bio, Global Blood Therapeutics
• Portfolio size: 143 investments

You can refer to their website here.

13. Springbank Collective

Springbank Collective is an early-stage investment firm based in New York that funds the infrastructure needed to support women and working families.

The firm's portfolio shows a clear commitment to its theme, backing companies that address caregiving, financial management, and career advancement. They supported the women's executive network Chief to a unicorn valuation and also backed Wellthy, a platform that helps families manage care.

Springbank may be a good match if you are an early-stage founder building a business in consumer tech, fintech, or healthcare that directly serves women or working families. Their focused mission makes them a strong partner for founders seeking value-aligned capital.

• Investment stages: Seed and early stage
• Industries of focus: Consumer, FinTech, Health Care, and services for women and working families
• Geographical presence: New York, NY
• Founded: 2019
• Notable investments: Chief, Wellthy, and Copper
• Portfolio size: 41 investments
• Investor type: Venture capital and syndicate

You can refer to their website here.

14. TMV

TMV is a New York-based, early-stage venture firm that invests in companies shaping the future of how we live. They support purpose-driven founders building businesses in areas like healthcare, financial services, and the future of work.

The firm has a track record of backing high-profile, mission-oriented companies, including the primary-care provider Cityblock Health and the medical-apparel brand FIGS. Their focus is on businesses that create tangible improvements in people's daily lives.

TMV is a good fit for early-stage founders building companies with a strong mission in healthcare, fintech, or consumer technology. They are particularly well-suited for entrepreneurs who value a partner with experience scaling purpose-driven brands.

• Investment stages: Seed and early stage
• Industries of focus: Health Care, FinTech, Education, Future of Work
• Geographical presence: New York, NY
• Founded: 2016
• Notable investments: Cityblock Health, FIGS, Casper Sleep
• Portfolio size: 66 investments
• Investor type: Venture capital

You can refer to their website here.

15. Creative Ventures

Creative Ventures is a deep tech venture firm based in Oakland, investing in early-stage companies that aim to solve major global challenges. They focus on founders using science and engineering to address critical issues.

The firm's approach is centered on deep tech, backing companies with tangible, often hardware-based, solutions. Their portfolio includes the AI-powered retail company Caper and the quantum-computing startup Bleximo, showing a clear preference for complex technologies.

Creative Ventures is a good match for founders with deep technical or scientific expertise building businesses in sectors like advanced materials, robotics, or biotech. They are best suited for early-stage teams tackling difficult industrial or societal problems.

• Investment stages: Seed and early stage venture
• Industries of focus: Deep Tech, Health Care, Advanced Materials, Robotics, Clean Energy
• Geographical presence: Oakland, CA
• Founded: 2016
• Notable investments: Caper, Sense Photonics, Bleximo
• Portfolio size: 60 investments

You can refer to their website here.

What This Tells Us About The VC Scene for Healthcare Companies

This list shows that the healthcare sector attracts a wide range of investors. You’ll find that many prominent firms invest across the entire company lifecycle, from seed rounds to post-IPO. This balance is a positive sign for founders, as it indicates the potential for long-term partnerships that can support a company from its initial stages through to growth and exit.

Geographically, investment remains concentrated in major hubs like the Bay Area, Boston, and New York. The types of investors are also varied, including traditional VCs, corporate venture arms, and mission-focused funds. This variety gives you more options to find a partner whose model and values align with your company's goals. We hope this guide provides a solid starting point for your research.

Raise Confidently with Rho

Fundraising requires significant time and energy, making a focused list of investors invaluable. It helps you direct your efforts toward the firms most likely to be a good fit for your company.

If you’ve just raised, Rho can help you set up your financial stack in minutes. We make it simple to get your company's finances organized from day one.

We provide the tools you need to manage your new capital with confidence. Our platform offers integrated business banking, corporate cards, and automated bill pay for growing startups.

FAQs about Venture Capital Firms Focused on Healthcare

How do medical device VC firms evaluate startups?

They focus on the device's clinical utility, regulatory pathway, intellectual property protection, and market size. A clear reimbursement strategy and a strong engineering team are also critical factors for securing investment from medical device venture capital firms.

Are there venture capital firms that focus on mental health?

Yes, mental health is a growing area of interest for many VCs. While some large firms invest in it, specialized funds are also appearing that focus exclusively on mental and behavioral health technology and services for patients.

What is the difference between a life science and a digital health VC?

Life science VCs typically fund companies in biotech and pharmaceuticals, focusing on deep science and clinical trials. Digital health VCs back technology-first companies, such as those in telehealth, health IT, and patient engagement software platforms.

Why do some healthcare venture capital firms invest in all stages?

Investing across all stages allows a firm to support a company throughout its entire lifecycle. This model provides consistent capital and guidance from seed to IPO, creating a long-term partnership and maximizing the firm's potential return on investment.

How can Rho help my startup manage its new funding?

Once you've raised, we help you manage your new capital with confidence. Our platform offers integrated banking, corporate cards, and automated bill pay, giving you clear financial control from day one.