14 Leading Digital Health Angel Investors to Know

For founders raising capital in Digital Health and HealthTech, identifying the right investors is a critical first step.

Unlike venture capital firms, angel investors often write the first checks and can provide direct mentorship, making them valuable early partners.

To help you find a good match, we've created this guide to some of the most active angel investors in the space.

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Top Digital Health Angel Investors By Stage

Many digital health angels invest at the pre-seed and seed stages, where their capital and experience can have the greatest impact. Understanding which investors are active at your company's stage will help you focus your fundraising efforts.

Pre-seed Angel Investors in Digital Health

Pre-seed is the earliest funding stage, typically used to refine your business idea and build a minimum viable product. Investors active at this stage include Brian Reilly, David Tisch, and Ramanan Raghavendran.

Seed Stage Angel Investors in Digital Health

Seed funding helps startups establish market fit and begin scaling their team and operations, and it's a common entry point for angel investors. For digital health companies at this stage, investors like Blake Mycoskie, Enrique Allen, and Anton Levy are worth looking into.

Series A Angel Investors in Digital Health

Series A funding is for companies with a proven product and consistent revenue, used to scale operations and expand market reach. Among the investors in our list who participate in Series A rounds are Brett Brewer, Mark Dzialga, and Jim Tananbaum.

Series B Angel Investors in Digital Health

Series B funding is focused on scaling the company to meet growing demand and expanding into new markets. Notable investors for Series B rounds in digital health include Christopher Dean, William Ford, and Thomas Jennings.

Keep in mind that many investors are flexible and participate in rounds across different stages.

For example, Vijay Pande and Dave Barrett have investment experience from Seed to Series B, making them potential partners for companies at various points in their growth.

Below, we offer a closer look at some of the top angel investors in digital health. We've included details on their typical investment stages, areas of interest, location, and what makes each one a compelling partner for founders.

1. Christopher Dean

As a Managing Director at Summit Partners, Christopher Dean is involved in growth equity investments, which often means he participates in larger rounds than a typical angel investor. His background gives him experience across a wide spectrum of technology and healthcare companies.

A key characteristic of his investment profile is the breadth of stages he covers, from Seed to Series B, with a significant investment range of $5.0M to $50.0M. While he has interests in Digital Health and BioTech, his portfolio also includes companies like the e-commerce brand Brooklinen, showing a broad appetite for high-growth businesses.

He could be a great match for founders whose companies have demonstrated traction and are ready for a significant capital injection to scale. His experience in later-stage rounds suggests he can support companies through major growth phases.

• Investment stages: Seed, Series B
• Sectors of focus: Digital Health, BioTech, FinTech, E-commerce, Health IT
• Geographical presence: Boston, Massachusetts
• Ideal investment range: $5.0M - $50.0M
• Notable investments: ShipMonk, Brooklinen, Celcoin

You can find more information about Christopher Dean on his LinkedIn or the firm's website.

2. William Ford

As the CEO of General Atlantic, William Ford operates at the growth equity level, meaning he's involved in much larger investment rounds than a typical angel. He is known for leading a global firm that backs companies with proven track records and significant growth potential.

A defining characteristic of his investment approach is a focus on the Series B stage, with a substantial investment range of $20.0M to $100.0M. His portfolio includes major international players like Reliance Jio and IHS Markit, indicating an interest in businesses that are already leaders in their respective markets.

Ford is an ideal match for founders whose companies have moved beyond the startup phase and are seeking major capital to scale globally. If your digital health company has strong market traction and is ready for its next major growth phase, his firm could be a valuable partner.

• Investment stages: Series B
• Sectors of focus: Digital Health, Health IT, FinTech, Retail, Marketplaces
• Geographical presence: New York City
• Ideal investment range: $20.0M - $100.0M
• Notable investments: Reliance Jio, Reliance Retail, IHS Markit

You can find more information about William Ford on his LinkedIn or the firm's website.

3. Blake Mycoskie

Blake Mycoskie is best known as the founder of TOMS and an active angel investor. He invests personally rather than through a large firm, bringing his direct experience as a founder to the table.

A key aspect of his investment approach is a focus on mission-driven, consumer-facing brands, as seen in his own ventures and portfolio companies like Athletic Brewing. He primarily invests at the seed stage, writing smaller checks to help founders get started.

He is a great match for early-stage founders building companies with a strong brand story and a social or wellness component. Founders who would benefit from a mentor with deep experience in building a global, mission-oriented brand will find him a valuable partner.

• Investment stages: Seed
• Sectors of focus: Digital Health, BioTech, Health & Hospital Services, Fashion
• Geographical presence: Los Angeles, California
• Ideal investment range: $5K - $50K
• Notable investments: Athletic Brewing, Liquid Death, TARA Mind

You can find more information about Blake Mycoskie on his LinkedIn or personal website.

4. Thomas Jennings

As a Managing Director at Summit Partners, Thomas Jennings is a growth equity investor with a long track record in the healthcare and technology sectors. He has been with the firm since 1997, bringing decades of experience to companies ready for their next stage of growth.

A defining feature of his investment approach is a clear focus on the Series B stage, with a substantial investment sweet spot of around $20.0M. His interest spans across Digital Health, Health IT, and BioTech, indicating a preference for companies that have already established a solid foundation and are prepared to scale.

Jennings could be a great partner for founders whose companies have proven their model and are seeking significant capital for expansion. If your digital health business is targeting a Series B round, his experience in guiding growth-stage companies could be a major asset.

• Investment stages: Series B
• Sectors of focus: Digital Health, Health IT, BioTech, Health & Hospital Services, SMB Software
• Geographical presence: Boston, Massachusetts
• Ideal investment range: $5.0M - $50.0M
• Notable investments: Accedian, PeerApp

You can find more information about Thomas Jennings on his LinkedIn or the firm's website.

5. Anton Levy

As a key figure at General Atlantic, Anton Levy is a growth equity investor who backs companies across the technology spectrum. He operates at a scale that involves significant capital, focusing on businesses with the potential for substantial growth.

His investment approach is marked by a wide range of interests, from FinTech and Enterprise software to Digital Health and BioTech. While he participates in both Seed and Series A rounds, his investment range of $20.0M to $100.0M indicates a focus on companies that are ready for major scaling, with notable investments in companies like Squarespace and Bolt.

Levy is a good match for founders who have already established a strong product and are seeking a large capital injection to accelerate growth. If your company operates in a high-growth tech sector and is prepared for a significant partnership, his firm's resources could be a powerful asset.

• Investment stages: Seed, Series A
• Sectors of focus: Digital Health, FinTech, Enterprise, Consumer Health, BioTech
• Geographical presence: New York, New York
• Ideal investment range: $20.0M - $100.0M
• Notable investments: Squarespace, Bolt, Chronosphere, HiBob

You can find more information about Anton Levy on his LinkedIn or the firm's website.

6. Vijay Pande

As a General Partner at Andreessen Horowitz (a16z), Vijay Pande leads the firm's investments in companies combining biology and computer science. His background is distinctive, blending a distinguished academic career at Stanford with founding the Folding@home distributed computing project.

A key characteristic of his investment approach is a focus on "bio + tech," backing companies that apply computational methods to solve complex biological problems. His portfolio, which includes companies like BioAge Labs and Asimov, reflects this interest, and he is active across multiple funding stages from Seed to Series B.

Pande is an excellent match for founders with deep scientific or technical expertise who are building businesses based on fundamental research. If your company is working on a complex problem in health or biology and needs a partner who understands the science, he could be a powerful ally.

• Investment stages: Seed, Series A, Series B
• Sectors of focus: Digital Health, BioTech, Health IT, Pharmaceuticals, Health & Hospital Services
• Geographical presence: San Francisco, California
• Ideal investment range: $100K - $10.0M
• Notable investments: Devoted Health, BioAge Labs, Levels, Asimov

You can find more information about Vijay Pande on his firm's website or LinkedIn.

7. Brian Reilly

Brian Reilly is an investor at Will Ventures, where he concentrates on early-stage companies. His work often centers on the intersection of health, wellness, and technology, making him a key figure for founders in those spaces.

A primary characteristic of his approach is a commitment to the earliest stages of a company's life, investing in Pre-seed and Seed rounds. His portfolio shows an interest in companies that blend technology with consumer wellness and sports, as seen in investments like Ness and Aktivate.

He could be a great match for founders building companies in the digital health, wellness, or sports tech sectors. If you're at the pre-seed or seed stage and need a partner who understands consumer-facing technology, he is worth reaching out to.

• Investment stages: Pre-seed, Seed
• Sectors of focus: Digital Health, Wellness & Fitness, Health IT, AI, Entertainment & Sports
• Geographical presence: Brooklyn, New York
• Ideal investment range: $100K - $5.0M
• Notable investments: Ness, Aktivate

You can find more information about Brian Reilly on his LinkedIn or the firm's website.

8. David Tisch

As a Managing Partner at BoxGroup and a co-founder of TechStars NYC, David Tisch is a central figure in New York's early-stage investment scene. He is known for backing companies from their earliest days, often well before they have a proven product.

A key aspect of his investment style is his breadth, covering sectors from Digital Health and FinTech to Marketplaces and Enterprise software. He is active from Pre-seed to Series A, and his involvement with companies like Ro and Arcadia shows a history of identifying and supporting businesses that go on to achieve significant scale.

Tisch is an ideal partner for founders at the pre-seed and seed stages who are looking for more than just capital. His experience with TechStars and Cornell Tech indicates a commitment to mentorship and founder support, making him a valuable ally for those just starting out.

• Investment stages: Pre-seed, Seed, Series A
• Sectors of focus: Digital Health, FinTech, Marketplaces, Enterprise, Health IT
• Geographical presence: New York, New York
• Ideal investment range: $250K - $1M
• Notable investments: Ro, Arcadia, Vial, Nourish

You can find more information about David Tisch on his personal website or LinkedIn.

9. Enrique Allen

Enrique Allen is a co-founder and General Partner at Designer Fund, a venture capital firm that invests in design-led companies. His background as a founder and his role at the firm mean he brings both operational experience and a specific investment thesis to the table.

A defining trait of his investment approach is a focus on companies where design is a core part of the business strategy. He primarily invests at the Seed stage, backing founders across a variety of sectors including Digital Health, ClimateTech, and Consumer Internet.

Allen is a great match for early-stage founders who believe that strong design and user experience are critical competitive advantages. If you are building a design-centric company and are raising a seed round, he could be a valuable partner.

• Investment stages: Seed
• Sectors of focus: Digital Health, ClimateTech/CleanTech, Marketplaces, Consumer Internet
• Geographical presence: San Francisco, California
• Ideal investment range: $100K - $1M
• Notable investments: Flatfile, Dopt

You can find more information about Enrique Allen on his LinkedIn or the firm's website.

10. Dave Barrett

As a managing partner at Polaris Partners, Dave Barrett focuses on technology and healthcare investments. His position within a venture firm allows him to bring substantial resources and a broad network to the companies he supports.

A key characteristic of his investment style is his activity across multiple funding stages, from Seed to Series B. His portfolio, which includes companies like Cohere Health and OM1, demonstrates a strong interest in health IT, data services, and SaaS.

Barrett is a great match for founders building technology-first companies in healthcare and enterprise software. If you are raising a Seed, Series A, or Series B round and need a partner with experience scaling complex tech businesses, he could be a valuable ally.

• Investment stages: Seed, Series A, Series B
• Sectors of focus: Digital Health, Health IT, SaaS, FinTech, Data Services
• Geographical presence: Boston, Massachusetts
• Ideal investment range: $300K - $2.0M
• Notable investments: Cohere Health, Tausight, OM1, Simon Data

You can find more information about Dave Barrett on his LinkedIn or the firm's website.

11. Ramanan Raghavendran

As a Managing Partner at Amasia, Ramanan Raghavendran brings a wealth of experience from his time at firms like General Atlantic and Insight Venture Partners. He is a seasoned investor who primarily focuses on backing companies at their earliest stages.

A key characteristic of his investment style is its breadth, covering sectors from Digital Health and FinTech to ClimateTech and SaaS. This wide-ranging interest, reflected in a portfolio that includes companies like Xendit and Joro, suggests a focus on strong founding teams over a narrow industry thesis.

Raghavendran is an excellent match for pre-seed and seed-stage founders who are looking for a partner with deep experience across multiple venture firms and market cycles. His firm's focus on cross-border businesses makes him particularly relevant for companies with global ambitions.

• Investment stages: Pre-seed, Seed
• Sectors of focus: Digital Health, FinTech, ClimateTech/CleanTech, SaaS, E-commerce
• Geographical presence: San Francisco, California
• Ideal investment range: $100K - $5.0M
• Notable investments: Xendit, Joro, Living Food, ClimateTrade

You can find more information about Ramanan Raghavendran on his personal website or LinkedIn.

12. Jim Tananbaum

As the founder and CEO of Foresite Capital Management, Jim Tananbaum is a seasoned investor with a focus on healthcare and life sciences. He brings a unique perspective shaped by his own experience as a founder, having co-founded GelTex, which was acquired for $1.6 billion.

His background is distinguished by a combination of an MD from Harvard, an MS from MIT, and an MBA from Harvard, giving him a deep scientific and business foundation. This expertise is evident in his investments in technically complex companies like Element Biosciences and Alumis, and his willingness to invest across Seed, Series A, and Series B rounds.

Tananbaum is an ideal partner for founders with a strong scientific or technical background who are building companies in the biotech and life sciences space. His ability to support a company from its early stages through significant growth phases makes him a compelling long-term ally.

• Investment stages: Seed, Series A, Series B
• Sectors of focus: Health & Hospital Services, Digital Health, Consumer Health, BioTech, Health IT
• Geographical presence: San Francisco, California
• Ideal investment range: $100K - $5.0M
• Notable investments: Element Biosciences, Alumis, DNAnexus, ImmPACT Bio

You can find more information about Jim Tananbaum on his LinkedIn or the firm's website.

13. Brett Brewer

As a managing partner at CrossCut, a California-based venture capital firm, Brett Brewer is an active early-stage investor. He primarily backs companies at the Seed and Series A stages across a variety of technology sectors.

A key characteristic of his investment approach is its breadth, with interests ranging from Digital Health and SaaS to E-commerce and AI. His portfolio, which includes companies like Omaze and The Black Tux, shows a history of supporting both consumer and enterprise businesses from their early days.

Brewer could be a good partner for founders raising a Seed or Series A round in a number of different technology sectors. His experience across various business models makes him a versatile investor for teams ready to scale.

• Investment stages: Seed, Series A
• Sectors of focus: Digital Health, SaaS, E-commerce, Real Estate/PropTech, AI
• Geographical presence: Turlock, California
• Ideal investment range: $100K - $5.0M
• Notable investments: Omaze, The Black Tux, Branch, Rx Redefined

You can find more information about Brett Brewer on the firm's website or his Crunchbase profile.

14. Mark Dzialga

As the founder and Managing Partner of Brighton Park Capital, Mark Dzialga is a growth equity investor with extensive experience backing technology companies. Before starting his own firm, he spent over two decades at General Atlantic, where he honed his expertise in identifying and scaling high-growth businesses.

A defining characteristic of his investment approach is the significant capital he provides, with a range of $20.0M to $150.0M, targeting companies ready for their next major phase. His firm has an interest in sectors like Health IT and SMB Software, with investments in companies such as NuORDER and MathCo.

Dzialga is an ideal partner for founders whose companies have established product-market fit and are seeking a large capital injection for expansion. If you are raising a Series A or later and need a partner with a long track record in scaling enterprise technology businesses, his firm is worth considering.

• Investment stages: Seed, Series A
• Sectors of focus: Health & Hospital Services, Digital Health, Consumer Health, Health IT, SMB Software
• Geographical presence: New York, New York
• Ideal investment range: $20.0M - $150.0M
• Notable investments: NuORDER, MathCo, HTEC

You can find more information about Mark Dzialga on the firm's website or his LinkedIn.

What Startup Founders Should Look for in a Digital Health Investor

Finding the right digital health investor goes beyond securing capital; it’s about finding a partner who aligns with your company's stage and vision. As our list illustrates, investors have different specialties. Some focus on early-stage, mission-driven brands, while others from large firms engage in later, growth-focused rounds.

You may notice many of these investors are based in major hubs like New York City and Boston. It's also common for their interests to extend into adjacent fields such as biotechnology and FinTech. This diverse experience can be a significant asset, offering broader market insights and a more extensive network.

When evaluating potential partners, consider what your startup needs most. Are you looking for a hands-on mentor with direct operational experience, or the institutional support of a growth equity firm? Your answer will help you narrow your search and focus your outreach on the investors who are the best fit for your specific journey.

Raise Confidently with Rho

Fundraising is a demanding process, and your time is one of your most valuable resources. A focused list of potential partners helps you direct your energy where it will have the greatest effect.

Once you've secured capital, Rho can help you set up your financial stack in minutes. We offer integrated business banking, corporate cards, and bill pay to manage your new funds efficiently.

This ensures your angel capital is directed toward growth and operations, rather than being lost to manual financial admin.

FAQs about Digital Health Angel Investors

Are there digital health angel investors outside of major hubs like New York and San Francisco?

Yes, while major cities have high concentrations of investors, thriving tech ecosystems exist across the country. Founders can find active angel investors in Austin, Chicago, and other growing cities who are interested in digital health opportunities.

How should I pitch an angel who also invests in SaaS?

Emphasize the recurring revenue models and scalable technology platform of your digital health company. Highlighting strong unit economics will resonate with investors experienced in SaaS business models, showing them a familiar path to growth.

What is the difference between an angel and a VC at the seed stage?

Angel investors typically invest their own money and may offer more hands-on mentorship. Seed-stage VCs invest from a fund, often writing larger checks and focusing on metrics that support a path to future funding rounds.

What metrics matter most to early-stage digital health investors?

Early on, investors look for signs of product-market fit, such as user engagement and pilot program success. A clear regulatory pathway and a strong founding team are also critical for early-stage investors to see a viable path forward.

Are there digital health angel investors in Los Angeles?

Absolutely. Los Angeles has a growing community of angel investors interested in health and wellness startups. The city's blend of tech and media creates unique opportunities for consumer-focused health companies to find early-stage backing.

How can Rho help after I secure angel funding?

Once your funding is secured, we help you manage it effectively. Rho provides an all-in-one platform with business banking, corporate cards, and automated payables, so you can focus on growing your business.